Researchers from Universiti Sains Malaysia showcased a microbiome-based healthcare innovation at the International Invention, Innovation and Technology Exhibition 2026 (ITEX 2026), highlighting the global shift towards sustainable and biology-driven solutions in combating antimicrobial resistance (AMR).
A key highlight was Lassica K014™, a smart postbiotic innovation developed by Associate Professor Dr. Tan Joo Shun and his team from the School of Industrial Technology, USM. The technology is derived from Lactiplantibacillus plantarum K014, isolated from fermented cabbage, and is designed to restore microbial balance while suppressing harmful pathogens.
Laboratory findings showed that Lassica K014™ achieved over 90 percent inhibition against several clinically significant bacteria and fungi, including resistant strains. Unlike conventional antibiotics that focus solely on killing pathogens, this innovation works by strengthening the microbiome ecosystem, promoting healthier biological balance within the body.
Beyond antimicrobial activity, the technology demonstrates potential in improving gut health, reducing gastrointestinal discomfort, and supporting treatment for inflammatory skin conditions such as eczema linked to Staphylococcus aureus. Its strong heat and pH stability further enhances its suitability for industrial-scale production and commercial applications.
According to USM Vice-Chancellor Prof. Dato’ Seri Ir. Dr. Abdul Rahman Mohamed, the innovation reflects the university’s commitment to impactful, sustainable research that addresses pressing global health challenges.
The achievement underscores the growing importance of microbiome science and biotechnology in developing next-generation therapeutic strategies against AMR.
