Researchers at the University of Queensland (UQ) have reported advancements in the development of a chemical-free solution for managing flystrike in sheep through a technology known as BenPol. Flystrike, which occurs when live sheep are infested by maggots, represents a significant challenge in Australia, with control measures involving chemical pesticides costing around $320 million annually.
Importance of Chemical-Free Alternatives
Dr. Karishma Mody, a Research Fellow at the Queensland Alliance for Agriculture and Food Innovation (QAAFI), noted the necessity of creating chemical-free alternatives to promote sustainability within the wool industry. Prior research indicated that double-stranded RNA (dsRNA) could inhibit maggot development and lead to larval mortality. However, the rapid degradation of dsRNA in biological fluids has limited its practical application.
Introducing BenPol Technology
The BenPol technology provides a protective encapsulation for dsRNA, ensuring its integrity until it is consumed by larvae. This enables the dsRNA to reach the gut, where it can disrupt targeted genes. According to QAAFI PhD candidate Yakun Yan, BenPol presents a promising platform for enhancing the uptake of RNA technology in livestock.
Significance of Research Findings
These findings represent a significant step forward in the development of RNA-based strategies for livestock protection. Dr. Mody emphasized the importance of collaboration with the Department of Primary Industries (DPI) in successfully testing the BenPol platform, which involved sourcing blowfly eggs and larvae for laboratory experiments.
Future Directions
The research team is currently preparing for field trials involving sheep to assess the adaptation of BenPol for practical agricultural use. Dr. Mody highlighted that partnerships with industry stakeholders will be critical to ensure the technology can effectively preserve dsRNA in farming environments, potentially offering solutions to additional pest-related challenges in livestock, including tick infestations in cattle.
Publication Reference
The details of this research were published in the journal *Pest Management Science*.
(Source: University of Queensland)
