Chulalongkorn University’s Nano-Herbs Dental Spray for Dogs Awarded Bronze Medal at Innovation Exhibition in Switzerland
Chulalongkorn University’s “Nano-Herbs Dental Spray,” designed for dogs, has been awarded a Bronze Medal and the NRCT Honorable Mention Award at the 50th International Exhibition of Inventions Geneva, held on April 13, 2025. This recognition emphasizes the product’s potential to enhance oral health in pets.
A Solution for Periodontitis
The spray, developed by Professor Dr. Nopadon Pirarat from the Department of Pathology in the Faculty of Veterinary Science, aims to combat periodontitis, a prevalent condition in small-breed dogs, with an occurrence rate of 80-90% in dogs over the age of three. Untreated periodontitis can lead to serious health complications, including tooth loss and infections that may affect other organs.
Innovative Herbal Ingredients
The research team, including Dr. Kochakorn Sawaspakdee, Dr. Jakkawarn Yosthawornkul, and Dr. Sirinun Pisamai Tabtieang, focused on formulating a dental spray utilizing natural herbal ingredients. The product features alpha-mangostin, extracted from mangosteen peel, and clove oil, both recognized for their antibacterial and anti-inflammatory properties. The spray uses a delivery system based on nanotechnology known as “Nanostructured Lipid Carriers,” which enhances the absorption and effectiveness of the herbal components.
Clinical Trial Success
Clinical trials involving canine gum tissues indicated that the nanoparticles in the spray could penetrate more deeply than traditional methods, offering a safer and more effective treatment option for dogs. The findings suggested that the spray effectively inhibits harmful bacteria associated with periodontal diseases, representing a significant advancement in veterinary oral healthcare.
Future Plans and Commercialization
Currently, the product is in the prototyping phase and is undergoing testing on dogs with dental issues. There are plans to explore its application on other animal species to address bacterial diseases more broadly. The research team is actively pursuing commercialization and has filed a patent application for this innovative solution.
Collaborative Support
Collaborative efforts for this project include support from the National Research Council of Thailand (NRCT), the National Nanotechnology Center (NANOTEC), and Université Paris Cité, highlighting its international relevance in the veterinary field.
(Source: Chulalongkorn University)
