IPB University Highlights Wolbachia Mosquito Technology as a Game Changer in Combating Dengue Fever Outbreaks

An increase in cases of dengue hemorrhagic fever (DHF) during the rainy season has raised significant concerns for the Indonesian Ministry of Health. In response, various preventive measures are being implemented, including the introduction of Wolbachia mosquito technology, which has been recognized for its potential to reduce the spread of the dengue virus.
Effectiveness of Wolbachia Technology
According to Prof. Dr. Upik Kesumawati Hadi, an entomologist at IPB University, Wolbachia mosquito technology has been effectively utilized in multiple countries to decrease the incidence of dengue fever. Countries such as Australia, Vietnam, Brazil, Colombia, Honduras, El Salvador, and Singapore have reported successes in implementing this technology, resulting in notable reductions in dengue cases.
Case Study: Yogyakarta
In Indonesia, Yogyakarta presents a significant example, where the use of Wolbachia technology reportedly resulted in a 77% decrease in dengue fever cases and an 86% reduction in hospitalizations in 2022. Prof. Hadi noted that this approach was recommended by the World Health Organization’s Vector Control Advisory Group in 2023 as an effective strategy for managing dengue fever.
Government Initiatives
The Indonesian government has initiated pilot projects in five cities—West Jakarta, Bandung, Semarang, Bontang, and Kupang—utilizing Wolbachia mosquito technology. The outcomes of these projects are expected to be evaluated over the next one to two years.
How Wolbachia Technology Works
The efficacy of Wolbachia technology is based on its ability to disrupt the dengue virus’s replication process within Aedes aegypti mosquitoes. The modified mosquitoes are unable to transmit the disease after feeding on infected individuals because the virus is deprived of essential nutrients for its reproduction. This technology aims to mitigate the transmission capabilities of Aedes aegypti mosquitoes.
Biological Process Explained
Prof. Hadi clarified that this method does not involve genetic engineering, as the modified mosquitoes are produced from eggs that have been conditioned by Wolbachia bacteria. This process ensures that neither the mosquitoes nor the bacteria themselves are genetically modified.
Timeframe for Impact
However, the introduction of Wolbachia mosquitoes may not yield immediate benefits. A population of modified mosquitoes must reach approximately 60% of the local wild mosquito population before observable impacts are noted. This population is expected to increase to 100% through natural reproduction, allowing for the replacement of wild mosquitoes with those affected by Wolbachia.
Importance of Public Health Efforts
Despite the promising aspects of this technology, Prof. Hadi emphasized the continued importance of public health efforts. Personal and environmental hygiene practices are vital in disrupting the life cycle of Aedes aegypti mosquitoes and controlling the dengue virus.
Community Engagement Initiatives
Long-standing government initiatives, such as the “3M Plus Movement,” which promotes draining, covering, and recycling, have proven effective but require increased public participation for significant outcomes. The “1 House 1 Jumantik” movement is also aimed at encouraging households to eliminate mosquito breeding sites, though it encounters similar challenges in engaging the community.
Conclusion
As the Wolbachia technology is tested and rolled out, the effectiveness of the program will depend on both the technological advancements and sustained public health campaigns to control dengue fever in Indonesia.
Source: IPB University News